University Hospitals Birmingham NHS Foundation Trust

Medicines A–Z

M

Status Drug name NICE TAs Comments
Status: Green Metoclopramide tablets

Not recommended for patients aged 20 years and below due to risk of dystonic reactions.

MHRA guidance - metroclopramide: risk of neurological adverse effects

Status: Green Metoclopramide tablets#4.6
Status: Amber Metolazone

Specialist recommendation (unlicensed).

There is now a UK licensed metolazone 5mg tablet available (Xaqua®). There are significant differences in bioavailability between Xaqua® and alternative unlicensed imported metolazone preparations.

Xaqua® tablets have up to approximately twice the bioavailability of other metolazone preparations.

If switching from another metolazone product to Xaqua® tablets or vice versa, a dose adjustment may be necessary, and individualised titration based on patient's response and tolerability is advised.

More information available from Specialist Pharmacy Service (SPS). We are awaiting guidance on switching to the licensed product – in the mean time please ensure that the patients are not inadvertently switched between products.

Status: Red Metoprolol injection

Hospital only

Status: Green Metoprolol M/R tablets
Status: Green Metoprolol tablets
Status: Green Metranidazole gel 0.75% (Zidoval)
Status: Green Metronidazole (Anabact) 0.75% gel

Malodorous tumours and skin ulcers

Status: Green Metronidazole 0.75% gel

Rozex for rosacea

Status: Red Metyrapone capsules
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