Medicines A-to-Z

Drug name	NICE TAs	Comments
Obeticholic acid (Ocaliva®)	TA443 - Obeticholic acid for treating primary biliary cholangitis	Off label use. Consultant initiation only (gastro use). Hospital only - in line with NICE TA443.
Obinutuzumab (Gazyvaro®)	TA343 - Obinutuzumab in combination with chlorambucil for untreated chronic lymphocytic leukaemia TA513 - Obinutuzumab for untreated advanced follicular lymphoma TA629 - Obinutuzumab with bendamustine for treating follicular lymphoma after rituximab	For hospital use only Off label use - for thrombotic thrombocytopenic purpura (TTP)
Ocrelizumab	TA533 - Ocrelizumab for treating relapsing-remitting multiple sclerosis
Ocriplasmin (Jetrea®) injection	TA297 - Ocriplasmin for treating vitreomacular traction	For hospital use only
Octaplas®		Alternative to Factor XI when it is unavailable
Octasa ® 1g suppositories
Octenisan antimicrobial wash lotion
Octenisan nasal gel		Where allergy to Bactroban® exists or there are supply issues with Bactroban®
Octreotide (Sandostatin LAR®) injection		Amber - palliative care use only Red - Oncology, acromegaly
Octreotide injection		For gastroenterology use - initiation by specialist