University Hospitals Birmingham NHS Foundation Trust

Chapters

Status Drug name NICE TAs Comments
Status: Red Adalimumab
Status: Amber Asacol M/R 400mg, 800mg
Status: Amber Azathioprine tablets

ESCA
Status: Amber Balsalazide

Consultant initiation - only when other agents have been ineffective
Status: Amber Budesonide (Budenofalk® ) Suppositories

Specialist recommendation
Status: Red Budesonide 1mg orodispersible tablets (Jorveza®)
Status: Amber Budesonide 2mg rectal foam (2mg per 1 metered dose) (Budenofalk®)

Approved to support the shortage of Colifoam (June 2018)
Status: Red Budesonide 9mg prolonged-release tablets (Cortiment®)
Status: Amber Budesonide capsules (Budenofalk capsules 3mg)

Consultant initiation only
Status: Red Budesonide MMX (Cortiment®)
Status: Red Ciclosporin intravenous

Hospital only - MHRA specify that oral ciclosporin must be prescribed and dispensed by brand as bioavailability differences exist between brands.
Status: Red Ciclosporin oral

Hospital only - MHRA specify that oral ciclosporin must be prescribed and dispensed by brand as bioavailability differences exist between brands.
Status: Amber Eluxadoline (Truberzi®)

To be used in line with NICE TA 471. Specialist initiation, and transfer prescribing to GP using RICaD (in development).
Status: Red Etrasimod
Status: Red Filgotinib (Jyseleca®)#1.5
Status: Grey Guselkumab (Tremfya®)

Please contact mmag@uhb.nhs.uk for advice
Status: Amber Hydrocortisone foam (Colifoam)
Status: Red Hydrocortisone injection
Status: Green Hydrocortisone tablets
Status: Red Infliximab
Status: Amber Mercaptopurine tablets

ESCA
Status: Amber Mesalazine (Octasa®)

Octasa is preferred brand of choice
Status: Amber Methotrexate tablets (2.5mg)

ESCA. Methotrexate tablets - use 2.5mg strength only. Methotrexate injection - Metoject is APC preferred brand. Check cytotoxic disposal arrangements locally.
Status: Amber Mezavant XL
Status: Red Mirikizumab  (Omvoh®)
Status: Red Mirikizumab (Omvoh®)
Status: Red Ozanimod (Zeposia®)
Status: Red Ozanimod (Zeposia®)
Status: Amber Pentasa 1g suppositories
Status: Amber Pentasa M/R 500mg
Status: Amber Prednisolone foam enema
Status: Amber Prednisolone retention enema
Status: Amber Prednisolone suppositories
Status: Green Prednisolone tablets

For exacerbations
Status: Grey Risankizumab (Skyrizi®)
Status: Amber Salofalk foam enema
Status: Amber Salofalk granules
Status: Amber Sulfasalazine
Status: Red Teduglutide (Revestive®)
Status: Red Tofacitinib (Xeljanz®)
Status: Red Upadacitinib (Rinvoq®)#1.5
Status: Red Ustekinumab (Stelara®)
Status: Red Vedolizumab
  • Hospital only - use in line with NICE
  • Off label use - for the treatment of refractory immunotherapy-related colitis
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