University Hospitals Birmingham NHS Foundation Trust

Chapters

Status Drug name NICE TAs Comments
Status: Red Arachis oil enema
Status: Green Bisacodyl
Status: Green Co-danthramer capsules

For terminally ill patients

Status: Green Co-danthramer suspension

For terminally ill patients

Status: Green Co-danthrusate capsules

For terminally ill patients

Status: Green Danthron

Treatment of constipation in terminally ill patients

Status: Green Docusate capsules
Status: Green Docusate liquid
Status: Red Fleet Phospho-Soda
Status: Green Glycerin suppositories
Status: Green Isphagula husk
Status: Red Klean prep
Status: Green Lactulose solution
Status: Amber Linaclotide

For moderate to severe IBS-Constipation. For patients who have not responded adequately to or cannot tolerate all other suitable treatment options BUT BEFORE other agents with higher costs.

Status: Green Macrogol sachets e.g. Laxido
Status: Green Micro-enema
Status: Amber Misoprostol

Specialist use only

Status: Red Moviprep

For radiology use

Status: Green Naldemedine (Rizmoic®)
Status: Green Naloxegol (Moventig®)

For treating opioid-induced chronic constipation - use in line with NICE

Status: Green Phosphate enema
Status: Red Picolax

Bowel cancer screening

Status: Red Plenvu®
Status: Amber Prucalopride

Available for use in men and women for chronic constipation.

Status: Green Senna syrup
Status: Green Senna tablets
Status: Green Sodium citrate enema
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