University Hospitals Birmingham NHS Foundation Trust

Chapters

Status Drug name NICE TAs Comments
Status: Amber Acenocoumarol tablets
Status: Amber Apixaban#Amber

Specialist initiation for the treatment and secondary prevention of DVT and/or PE - use in line with NICE and supported by RICaD

Status: Green Apixaban#Green

Second choice following diagnosis of AF - use in line with NICE

Status: Red Apixaban#Red

Use following hip and knee surgery - full course of treatment supplied on discharge

Status: Red Argatronban
Status: Red Bivalirudin 250mg injection

Hospital use only

Status: Amber Dabigatran capsules

Following diagnosis of AF – use in line NICE and toolkit, initiation/recommendation by haematologist, transfer to GP with RICaD. For the treatment and secondary prevention of DVT and/or PE - use in line with NICE. Initiation/recommendation by haematologist, transfer to GP with RICaD

Adults only

Status: Red Dabigatran capsules #2.8

Use following hip and knee surgery – full course of treatment supplied on discharge

Status: Red Danaparoid injection

Hospital use only

Status: Green Edoxaban

First choice following a diagnosis of AF - use in line with NICE

Status: Amber Edoxaban#Amber

Specialist initiation - For the treatment and secondary prevention of DVT and/or PE - use in line with NICE and supported by RICaD

Status: Red Enoxaparin Injection

For all other indications. The APC's view is that on clinical grounds, the status for certain indications approved by APC should be amber, supported by an ESCA. However, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain red (ESCAs to be developed). 

Status: Red Epoprostenol injection

Hospital use only

Status: Red Fondaparinux injection

Hospital use only

Status: Red Heparin sodium injection

Hospital use only

Status: Red Idarucizumab 2.5g/250ml solution for injection/infusion

When rapid reversal of Dabigatran anticoagulant effect is required

Status: Amber Phenindione tablets
Status: Red Protamine sulphate injection

Hospital use only

Status: Amber Rivaroxaban tablets
  • Amber - specialist initation following diagnosis of AF- use in line with NICE. Initiation/ recommendation by a clinician who routinely initiates anticoagulants
  • Amber - specialist initation for the treatment and secondary prevention of DVT and/or PE - use in line with NICE. Initiation/ recommendation by a clinician who routinely initiates anticoagulants. Where this is not the patient's GP, transfer to GP should be with the support of RICaD
  • Amber - specialist initiation for preventing adverse outcomes after acute management of ACS use in line with NICE TA335. Initiation/recommendation by a clinician who routinely initiates anticoagulants. Where this is not the patient's GP, transfer to GP should be with the support of RICaD
Status: Red Rivaroxaban tablets #2.8

BSSE APC preferred agent. This recommendation must only be taken into account after a patient and prescriber have discussed all treatment options (including warfarin) and only if they have no preference about which medicine they want to use.

Red use following hip and knee surgery – full course of treatment supplied on discharge

Status: Red Taurolock

Hospital use only

Status: Red Taurolock Hep 500

Hospital use only

Status: Amber Warfarin tablets

First choice. BSSE APC preferred agent. This recommendation must only be taken into account after a patient and prescriber have discussed all treatment options (including warfarin) and only if they have no preference about which medicine they want to use. To be initiated by those who have the appropriate skills and experience.

Use should be in line with local commissioning arrangements - for BCC CCG - Anticoagulation AQP. Ensure that patients prescribed anticoagulants receive appropriate verbal and written information at the start of therapy, at hospital discharge, on the first anticoagulant clinic appointment, and when necessary throughout the course of their treatment (NPSA Alert 18)

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