University Hospitals Birmingham NHS Foundation Trust

Chapters

Status Drug name NICE TAs Comments
Status: Green Amitriptyline

(Off label). Low abuse, low cost

Status: Green Amitriptyline#4.7

Anti-migraine

Status: Green Aspirin 300mg dispersible tablets

Topical analgesia - for gargling

Status: Red Aspirin suppositories
Status: Red Botox A
Status: Amber Buprenorphine patches

Specialist initiation only. Patches must be prescribed by brand.

Status: Red Buprenorphine S/L tablets

Specialist initiation only

Status: Amber Capsaicin cream 0.075%

Only strength licensed for post-herpetic neuralgia and diabetic peripheral polyneuropathy.

Status: Green Carbamazepine

Trigeminal neuralgia only

Status: Green Co-codamol 30/500 capsules

Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties.

Status: Green Co-codamol 30/500 effervescent tablets

Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties.

Status: Green Co-codamol 30/500 tablets

Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties.

Status: Green Codeine phosphate 25mg/5ml syrup
Status: Red Codeine phosphate 60mg/1ml injection
Status: Green Codeine phosphate tablets
Status: Green Diamorphine hydrochloride injection
Status: Green Dihydrocodeine solution

For patients with swallowing difficulties

Status: Green Dihydrocodeine tablets
Status: Red Dihydroergotamine IV
Status: Green Duloxetine
Status: Red Erenumab  (Aimovig®)
Status: Red Fentanyl injection
Status: Red Fentanyl lozenges

For palliative care use only

Status: Amber Fentanyl patches
Status: Red Fentanyl sublinual tablets

For palliative care use only

Status: Red Fetanyl nasal spray
Status: Red Flunarazine tablets

Not licensed in the UK. Licensed in Europe and Ireland - preventative management in primary headache.

Status: Red Fremanezumab (Ajovy®)
Status: Green Gabapentin capsules

Second line - please be aware of the abuse potential associated with this class of agent - see NHS England advice.

Status: Green Gabapentin tablets

Second line - please be aware of the abuse potential associated with this class of agent - see NHS England advice.

Status: Amber Lidocaine 5% patch

For patients who have been treated in line with NICE CG173 Neuropathic pain in adults: pharmacological management in non-specialist settings but are still experiencing neuropathic pain associated with previous herpes zoster infection (post-herpetic neuralgia)

Status: Red Meptazinol
Status: Red Meptazinol (Meptid®)

HGS only

Status: Red Methoxyflurane (Penthrox®)

For severe pain of traumatic origin and facilitation of management of significant fractures and dislocations

Status: Green Migraleve® pink
Status: Red Morphine sulphate 100mg/100ml PCA
Status: Green Morphine sulphate 100mg/5ml solution
Status: Green Morphine sulphate 10mg/5ml solution
Status: Red Morphine sulphate 5mg/5ml intrathecal injection

For West Midlands Rehab Unit only

Status: Green Morphine sulphate injection
Status: Green Morphine sulphate M/R capsules

Zomorph

Status: Green Morphine sulphate M/R sachets

MST continus

Status: Green Morphine sulphate M/R tablets
Status: Red Morphine sulphate suppositories
Status: Green Morphine sulphate tablets
Status: Amber Oxycodone hydrochloride capsules

Lynlor capsules preferred brand

Status: Red Oxycodone hydrochloride injection
Status: Amber Oxycodone hydrochloride M/R tablets

Reltebon MR tablets preferred brand

Status: Amber Oxycodone hydrochloride SF solution
Status: Red Paracetamol 1000mg/100ml infusion
Status: Green Paracetamol SF suspension
Status: Green Paracetamol soluble tablets

High sodium content - only if swallowing difficulties.

Status: Red Paracetamol suppositories
Status: Green Paracetamol tablets
Status: Red Pethidine injection
Status: Green Pizotifen elixir
Status: Green Pizotifen tablets
Status: Amber Pregabalin#4.7

4th line after duloxetine. Advice of specialist if duloxetine is unsuitable. Please be aware of the abuse potential associated with this class of agent - See NHS England advice. Prescribers should prescribe generically.

Status: Green Propranolol

Anti-migraine

Status: Grey Rimegepant
Status: Green Rizatriptan tablets

Reserved for patients who are vomiting due to migraine

Status: Green Sumatriptan 6mg/0.5ml syringe (plus auto-injector)
Status: Green Sumatriptan nasal spray
Status: Green Sumatriptan tablets
Status: Amber Topiramate tablets

Prophylaxis of migraine. Specialist recommendation.

Status: Green Tramadol capsules

Second line after morphine and codeine. Soluble tablets - high relative cost - patients with swallowing difficulties.

Status: Green Tramadol soluble tablets

Second line after morphine and codeine. Soluble tablets - high relative cost - patients with swallowing difficulties.

Status: Green Zolmitriptan

Tablets, orodispersible tablets and nasal spray

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