Chapters
Status | Drug name | NICE TAs | Comments |
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Amitriptyline |
(Off label). Low abuse, low cost |
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Amitriptyline#4.7 |
Anti-migraine |
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Aspirin 300mg dispersible tablets |
Topical analgesia - for gargling |
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Aspirin suppositories | ||
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Botox A | ||
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Buprenorphine patches |
Specialist initiation only. Patches must be prescribed by brand. |
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Buprenorphine S/L tablets |
Specialist initiation only |
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Capsaicin cream 0.075% |
Only strength licensed for post-herpetic neuralgia and diabetic peripheral polyneuropathy. |
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Carbamazepine |
Trigeminal neuralgia only |
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Co-codamol 30/500 capsules |
Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties. |
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Co-codamol 30/500 effervescent tablets |
Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties. |
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Co-codamol 30/500 tablets |
Wherever possible, avoid theu se of combination products. Use paracetamol and codeine separately. All combination products of paracetamol and codeine/dihydrocodeine are deemed products less suitable for prescribing in the BNF. Capsules have a very high relative cost. Sodium content. Only if swallowing difficulties. |
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Codeine phosphate 25mg/5ml syrup | ||
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Codeine phosphate 60mg/1ml injection | ||
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Codeine phosphate tablets | ||
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Diamorphine hydrochloride injection | ||
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Dihydrocodeine solution |
For patients with swallowing difficulties |
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Dihydrocodeine tablets | ||
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Dihydroergotamine IV | ||
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Duloxetine | ||
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Erenumab (Aimovig®) | ||
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Fentanyl injection | ||
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Fentanyl lozenges |
For palliative care use only |
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Fentanyl patches | ||
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Fentanyl sublinual tablets |
For palliative care use only |
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Fetanyl nasal spray | ||
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Flunarazine tablets |
Not licensed in the UK. Licensed in Europe and Ireland - preventative management in primary headache. |
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Fremanezumab (Ajovy®) | ||
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Gabapentin capsules |
Second line - please be aware of the abuse potential associated with this class of agent - see NHS England advice. |
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Gabapentin tablets |
Second line - please be aware of the abuse potential associated with this class of agent - see NHS England advice. |
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Lidocaine 5% patch |
For patients who have been treated in line with NICE CG173 Neuropathic pain in adults: pharmacological management in non-specialist settings but are still experiencing neuropathic pain associated with previous herpes zoster infection (post-herpetic neuralgia) |
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Meptazinol | ||
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Meptazinol (Meptid®) |
HGS only |
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Methoxyflurane (Penthrox®) |
For severe pain of traumatic origin and facilitation of management of significant fractures and dislocations |
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Migraleve® pink | ||
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Morphine sulphate 100mg/100ml PCA | ||
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Morphine sulphate 100mg/5ml solution | ||
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Morphine sulphate 10mg/5ml solution | ||
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Morphine sulphate 5mg/5ml intrathecal injection |
For West Midlands Rehab Unit only |
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Morphine sulphate injection | ||
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Morphine sulphate M/R capsules |
Zomorph |
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Morphine sulphate M/R sachets |
MST continus |
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Morphine sulphate M/R tablets | ||
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Morphine sulphate suppositories | ||
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Morphine sulphate tablets | ||
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Oxycodone hydrochloride capsules |
Lynlor capsules preferred brand |
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Oxycodone hydrochloride injection | ||
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Oxycodone hydrochloride M/R tablets |
Reltebon MR tablets preferred brand |
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Oxycodone hydrochloride SF solution | ||
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Paracetamol 1000mg/100ml infusion | ||
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Paracetamol SF suspension | ||
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Paracetamol soluble tablets |
High sodium content - only if swallowing difficulties. |
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Paracetamol suppositories | ||
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Paracetamol tablets | ||
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Pethidine injection | ||
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Pizotifen elixir | ||
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Pizotifen tablets | ||
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Pregabalin#4.7 |
4th line after duloxetine. Advice of specialist if duloxetine is unsuitable. Please be aware of the abuse potential associated with this class of agent - See NHS England advice. Prescribers should prescribe generically. |
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Propranolol |
Anti-migraine |
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Rimegepant | ||
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Rizatriptan tablets |
Reserved for patients who are vomiting due to migraine |
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Sumatriptan 6mg/0.5ml syringe (plus auto-injector) | ||
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Sumatriptan nasal spray | ||
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Sumatriptan tablets | ||
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Topiramate tablets |
Prophylaxis of migraine. Specialist recommendation. |
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Tramadol capsules |
Second line after morphine and codeine. Soluble tablets - high relative cost - patients with swallowing difficulties. |
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Tramadol soluble tablets |
Second line after morphine and codeine. Soluble tablets - high relative cost - patients with swallowing difficulties. |
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Zolmitriptan |
Tablets, orodispersible tablets and nasal spray |