University Hospitals Birmingham NHS Foundation Trust

Chapters

Status Drug name NICE TAs Comments
Status: Red Abemaciclib (Verzenios®)
Status: Red Acalabrutinib
Status: Red Afatinib
Status: Red Aflibercept

Hospital use only & negative TA
Status: Red Alpelisib
Status: Red Arsenic trioxide

Hospital use only
Status: Red Asciminib
Status: Red Asparaginase 10,000 units injection (5 vials)
Status: Red Atezolizumab (Tecentriq®)

Hospital use only
Status: Red Axitinib

National CDF list
Status: Red Azacitidine (Vidaza®)

For hospital use only
Status: Red Bendamustine injection
Status: Red Bevacizumab infusion (Avastin®)

Negative NICE TA & hospital use only.
Status: Red Bexarotene capsules
Status: Red Bleomycin injection

Hospital use only
Status: Red Blinatumomab

Hospital use only
Status: Red Bortezomib injection

National CDF list. Hospital use only.
Status: Red Bosutinib
Status: Red Brentuximab injection

National CDF list. For hospital use only.
Status: Red Brexucabtagene autoleucel
Status: Red Brigatinib (Alunbrig®)
Status: Red Busulfan tablets

For hospital use only
Status: Red Cabazitaxel infusion
Status: Red Cabozantinib
Status: Red Calcium folinate injection
Status: Red Calcium folinate tablets
Status: Red Capecitabine tablets
Status: Red Caplacizumab (Cablivi®)
Status: Red Carboplatin injection
Status: Red Carfilzomib

For hospital use only
Status: Red Carfilzomib (Kyprolis®)
Status: Red Carmustine 7.7mg implants

For hospital use only
Status: Red Carmustine injection

For hospital use only
Status: Red Cemiplimab
Status: Red Ceritinib

For hospital use only
Status: Red Cetuximab infusion

National CDF list. For hospital use only.
Status: Red Chlorambucil tablets
Status: Red Chlormethine gel
Status: Red Cisplatin

For hospital use only
Status: Red Cladribine injection

For hospital use only
Status: Red Clofarabine injection

For hospital use only
Status: Red Crisantaspase injection
Status: Red Crizanlizumab (Adakveo®)
Status: Red Crizotinib
Status: Red Cyclophosphamide injection

For hospital use only
Status: Red Cyclophosphamide tablets

For oncology
Status: Red Cyclophosphomide

Neurology indication
Status: Red Cytarabine injection

Funding approval should be sought before initiation
Status: Red Cytarabine liposomal injection

For hospital use only
Status: Red Cytarabine–daunorubicin liposomal (Vyxeos®)
Status: Red Dabrafenib
Status: Red Dabrafenib with trametinib
Status: Red Dacarbazine injection

For hospital use only
Status: Red Dacomitinib
Status: Red Dactinomycin injection

For hospital use only
Status: Red Daratumumab

Hospital use only
Status: Red Dasatinib tablets

Hospital use only
Status: Red Daunorubicin injection
Status: Red Daunorubicin liposomal injection
Status: Red Decitabine injection
Status: Red Dexrazoxane injection
Status: Red Docetaxel injection

Negative TA
Status: Red Doxorubicin injection
Status: Red Doxorubicin liposomal infusion

National CDF list
Status: Red Dupilumab
Status: Red Durvalumab
Status: Red Encorafenib (Braftovi®)
Status: Red Encorafenib with binimetinib
Status: Red Entrectinib
Status: Red Enzalutamide capsules
Status: Red Epirubicin injection

For hospital use only
Status: Red Epirubilin solution for injection
Status: Red Erlotinib tablets
Status: Red Etoposide tablets or capsules
Status: Red Everolimus (Afinitor®)

Negative outcome - CDF funded for renal, NET, breast. For hospital use only.
Status: Red Everolimus (Votubia®)

As recommended by NHSE

Refractory seizures associated with tuberous sclerosis
Status: Red Fedratinib (Inrebic®)
Status: Red Fludarabine injection
Status: Red Fludarabine tablets
Status: Red Fluorouracil injection

For hospital use only
Status: Red Gefitinib tablets
Status: Red Gemcitabine injection

Negative TA. Hospital use only.
Status: Red Glatiramer acetate (Copaxone®)
Status: Red Gliteritinib
Status: Red Glofitamab
Status: Amber Hydroxycarbamide capsules

For myeloproliferative disorders. ESCA under development
Status: Red Ibrutinib
Status: Red Idarubicin capsules
Status: Red Idarubicin injection

For hospital use only
Status: Red Idelalisib (Zydelig)
Status: Red Ifosfamide infusion

For hospital use only
Status: Red Imatinib (Glivec®)

Off-label use for melanoma with responsive c-KIT mutation 
Status: Red Ipilumumab injection
Status: Red Irinotecan injection

For hospital use only
Status: Red Isatuximab
Status: Red Ixazomib
Status: Red Lapatinib tablets

Negative TA
Status: Red Larotrectinib (Vitrakvi®)
Status: Red Lenvatinib (Kisplyx®)
Status: Red Lomustine capsules
Status: Red Lorlatinib (Lorviqua®)
Status: Red Melphalan injection

For hospital use only
Status: Red Melphalan tablets
Status: Red Mercaptopurine injection

For oncology
Status: Red Mercaptopurine tablets#8.1
Status: Red Mesna injection
Status: Red Mesna tablets
Status: Red Methotrexate 2.5mg tablets#8.1
Status: Red Methotrexate injection
Status: Red Midostaurin

For hospital use only
Status: Red Mifamurtide injection

For hospital use only
Status: Red Mitomycin injection

For hospital use only
Status: Red Mitotane tablets
Status: Red Mitoxantrone injection

For hospital use only
Status: Red Mobocertinib (Exkivity®)
Status: Red Mogamulizumab (Poteligeo®)
Status: Red Nab-paclitaxel
Status: Red Nelarabine vial
Status: Red Nilotinib capsules
Status: Red Nintedanib#8.1
Status: Red Niraparib
Status: Red Nivolumab (Opdivo®)
Status: Red Obinutuzumab (Gazyvaro®)
  • For hospital use only
  • Off label use - for thrombotic thrombocytopenic purpura (TTP)
Status: Red Olaparib (Lynparza®)
Status: Red Olaratumab

For hospital use only
Status: Red Osimertinib
Status: Red Oxaliplatin injection
Status: Red Paclitaxel
Status: Red Paclitaxel injection

Negative TA
Status: Red Palbociclib (Ibrance®)
Status: Red Palifermin injection

Private patients only
Status: Red Panitumumab concentrate for infusion

Negative TA
Status: Red Pazopanib tablets
Status: Red Pegaspargase injection

For hospital use only
Status: Red Pembrolizumab (Keytruda®)

For hospital use only
Status: Red Pemetrexed injection

For hospital use only. Negative TA (124)
Status: Red Pemigatinib
Status: Red Pentostatin injection

National CDF list
Status: Red Pertuzumab (Perjeta®)

For hospital use only
Status: Red Pixantrone

For hospital use only
Status: Red Polatuzumab (Polivy®)
Status: Red Ponatinib

For hospital use only
Status: Red Porfimer

HGS only
Status: Red Procarbazine capsules

National CDF list
Status: Red Ralititrexed injection

Hospital use only
Status: Red Regorafenib (Stivarga®)

For hospital use only
Status: Red Ribociclib (Kisqali®)

For hospital use only
Status: Red Rucaparib (Rubraca®)
Status: Red Ruxolitinib (Jakavi®)
Status: Red Sacituzumab govitecan
Status: Red Selpercatinib (Retsevmo®)
Status: Red Siponimod (Mayzent®)
Status: Red Sorafenib tablets

National CDF list. Negative outcome - CDF funded.
Status: Red Streptozocin injection

QEHB use only
Status: Red Sunitinib capsules

Hospital use only
Status: Red Temoporfin injection

National CDF list
Status: Red Temozolomide capsules
Status: Red Temsirolimus infusion (Torisel®)

Hospital use only
Status: Red Thiotepa injection

For hospital use only
Status: Red Tioguanine tablets
Status: Red Tisagenlecleucel (Kymriah®)
Status: Red Tivozanib
Status: Red Topotecan capsules

For hospital use only
Status: Red Trametinib
Status: Red Trastuzumab deruxtecan (Enhertu®)
Status: Red Trastuzumab emtansine
Status: Red Trastuzumab infusion

Funding approval should be sought prior to initiation
Status: Red Treosulfan capsules

National CDF list
Status: Red Treosulfan injection

For hospital use only
Status: Red Tretinoin capsules
Status: Red Vandetanib
Status: Red Vemurafenib tablets

National CDF list
Status: Red Venetoclax (Venclyxto®)

For hospital use only

And azacitidine for relapsed or refractory AML
Status: Red Vinblastine injection

For hospital use only
Status: Red Vincristine injection

For hospital use only
Status: Red Vindesine

HGS only
Status: Red Vinflunine

Negative TA
Status: Red Vinorelbine capsules
Status: Red Vinorelbine injection

For hospital use only
Status: Red Vismodegib

Commissioning to be confirmed prior to initiation
Status: Red Zanubrutinib
Status: Red Zanubrutinib (Brukinsa®)
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