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Drug name	NICE TAs	Comments
Pegfilgrastim injection		QEHB site only
Peginterferon Alfa-2A (Pegasys)		Myeloproliferative neoplasia (MPN)
Peginterferon Alfa-2B prefilled pen	TA75 - Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis C TA106 - Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis C TA300 - Peginterferon alfa and ribavirin for treating chronic hepatitis C in children and young people TA200 - Peginterferon alfa and ribavirin for the treatment of chronic hepatitis C TA96 - Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B
Peginterferon beta-1a	TA624 - Peginterferon beta-1a for treating relapsing–remitting multiple sclerosis
Pegunigalsidase alfa (Elfabrio®)
Pembrolizumab (Keytruda®)	TA357 - Pembrolizumab for treating advanced melanoma after disease progression with ipilimumab TA366 - Pembrolizumab for advanced melanoma not previously treated with ipilimumab TA428 - Pembrolizumab for treating PD-L1-positive non-small-cell lung cancer after chemotherapy TA519 - Pembrolizumab for treating locally advanced or metastatic urothelial carcinoma after platinum-containing chemotherapy TA522 - Pembrolizumab for untreated PD-L1-positive locally advanced or metastatic urothelial cancer when cisplatin is unsuitable TA531 - Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer TA540 - Pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma TA553 - Pembrolizumab for adjuvant treatment of resected melanoma with high risk of recurrence TA557 - Pembrolizumab with pemetrexed and platinum chemotherapy for untreated, metastatic, non-squamous non-small-cell lung cancer TA661 - Pembrolizumab for untreated metastatic or unresectable recurrent head and neck squamous cell carcinoma TA683 - Pembrolizumab with pemetrexed and platinum chemotherapy for untreated, metastatic, non-squamous non-small-cell lung cancer TA692 - Pembrolizumab for treating locally advanced or metastatic urothelial carcinoma after platinum-containing chemotherapy TA709 - Pembrolizumab for untreated metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency TA737 - Pembrolizumab with platinum- and fluoropyrimidine-based chemotherapy for untreated advanced oesophageal and gastro-oesophageal junction cancer TA801: Pembrolizumab plus chemotherapy for untreated, triple-negative, locally recurrent unresectable or metastatic breast cancer TA830: Pembrolizumab for adjuvant treatment of renal cell carcinoma TA837: Pembrolizumab for adjuvant treatment of resected stage 2B or 2C melanoma TA851 - Pembrolizumab for neoadjuvant and adjuvant treatment of triple-negative early or locally advanced breast cancer TA904 - Pembrolizumab with lenvatinib for previously treated advanced or recurrent endometrial cancer TA914 - Pembrolizumab for previously treated endometrial, biliary, colorectal, gastric or small intestine cancer with high microsatellite instability or mismatch repair deficiency TA939 - Pembrolizumab plus chemotherapy with or without bevacizumab for persistent, recurrent or metastatic cervical cancer Pembrolizumab with trastuzumab and chemotherapy for untreated locally advanced unresectable or metastatic HER2-positive gastric or gastro-oesophageal junction adenocarcinoma [TA983] Pembrolizumab with platinum- and fluoropyrimidine-based chemotherapy for untreated advanced HER2-negative gastric or gastro-oesophageal junction adenocarcinoma [TA997] Pembrolizumab with platinum- and fluoropyrimidine-based chemotherapy for untreated advanced oesophageal and gastro-oesophageal junction cancer [TA737] NICE TA 1092 Pembrolizumab with carboplatin and paclitaxel for untreated primary advanced or recurrent endometrial cancer NICE TA 1037 Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer NICE TA 1017 Pembrolizumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer	For hospital use only
Pemetrexed injection	TA190 - Pemetrexed for the maintenance treatment of non-small-cell lung cancer TA181 - Pemetrexed for the first-line treatment of non-small-cell lung cancer TA135 - Pemetrexed for the treatment of malignant pleural mesothelioma TA309 - Pemetrexed maintenance treatment following induction therapy with pemetrexed and cisplatin for non-squamous non-small-cell lung cancer TA124 - Pemetrexed for the treatment of non-small-cell lung cancer TA557 - Pembrolizumab with pemetrexed and platinum chemotherapy for untreated, metastatic, non-squamous non-small-cell lung cancer	For hospital use only. Negative TA (124)
Pemigatinib	TA722 - Pemigatinib for treating relapsed or refractory advanced cholangiocarcinoma with FGFR2 fusion or rearrangement
Penecillamine tablets		ESCA
Penicillamine		Specialist recommendation for Wilson disease. Supported with an ESCA (in development).

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University Hospitals Birmingham NHS Foundation Trust

Medicines Formulary

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