University Hospitals Birmingham NHS Foundation Trust

Status Drug name NICE TAs Comments
Status: Red Brexucabtagene autoleucel
Status: Red Brigatinib (Alunbrig®)
Status: Red Brimonidine 3mg/g (Mirvaso®)
Status: Amber Brinzolamide 1% and Brimonidine 0.2% eye drops (Simbrinza)

Specialist ophthalmologist recommendation

Status: Amber Brinzolamide eye drops

Specialist ophthalmologist recommendation

Status: Red Brivaracetam (Briviact ®) injection
Status: Amber Brivaracetam (Briviact®)

Initiation by Tertiary Epilepsy Specialist only. For adjunctive therapy in the treatment of partial-onset seizures with or without secondary generalisation in adult and adolescent patients from 16 years of age, with severe refractory epilepsy warranting tertiary specialist input for patients who have tried three or more AEDs. The patient has used levetiracetam and has documentation of intolerance and patient is using a third line agent (perampanel, zonisamide, lacosamide, eslicarbazepine) which would be replaced by brivaracetam. ESCA required.

Status: Red Brodalumab (Kyntheum®)
Status: Red Brolucizumab (Beovu®)
Status: Red Bromocriptine tablets
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