Medicines Formulary

Reports

Drug name	NICE TAs	Comments
Dapagliflozin (Forxiga®)	TA902 - Dapagliflozin for treating chronic heart failure with preserved or mildly reduced ejection fraction
Dapagliflozin	TA679 - Dapagliflozin for treating chronic heart failure with reduced ejection fraction
Dapagliflozin	TA597 - Dapagliflozin with insulin for treating type 1 diabetes	Specialist centres only for treating Type 1 diabetes
Daratumumab	TA510 - Daratumumab monotherapy for treating relapsed and refractory multiple myeloma TA573 - Daratumumab with bortezomib and dexamethasone for previously treated multiple myeloma TA897 - Daratumumab with bortezomib and dexamethasone for previously treated multiple myeloma TA917 - Daratumumab with lenalidomide and dexamethasone for untreated multiple myeloma when a stem cell transplant is unsuitable	Hospital use only
Darbepoetin alfa (Aranesp)	TA323 - Erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating anaemia in people with cancer having chemotherapy	NHSE commissioned renal dialysis. CCG commissioned for use in cancer - NICE TA323.
Darolutamide (Nubeqa®)	TA660 - Darolutamide with androgen deprivation therapy for treating hormone-relapsed non-metastatic prostate cancer TA903 - Darolutamide with androgen deprivation therapy and docetaxel for treating hormone-sensitive metastatic prostate cancer
Dasatinib tablets	TA425 - Dasatinib, nilotinib and high-dose imatinib for treating imatinib-resistant or intolerant chronic myeloid leukaemia TA426 - Dasatinib, nilotinib and imatinib for untreated chronic myeloid leukaemia	Hospital use only
Decitabine injection	TA270 - Decitabine for the treatment of acute myeloid leukaemia (terminated appraisal)
Degarelix injection	TA404 - Degarelix for treating advanced hormone-dependent prostate cancer	Supported by ESCA
Denosumab injection (Prolia®)	TA204 - Denosumab for the prevention of osteoporotic fractures in postmenopausal women	ESCA

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Drug status key

Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.

Red

Initiation and maintenance of prescribing by specialists only.

Amber

Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.

Green

Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.

Blue

Under review at University Hospitals Birmingham NHS Foundation Trust.