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        Multiple sclerosis relapse

        Relapses are caused by new inflammatory activity. They come on over a few hours to a few days and then take several weeks to improve.

        Relapses can be treated acutely with steroids, although this is not always needed.

        If patients have a relapse they may need to start or change immunomodulatory therapy, so they should let their MS nursing team know what has happened.

        Fluctuations in symptoms lasting just a few hours or days in patients with MS are usually caused by conduction block and would not need any further treatment or input.

        There are a few typical relapses which can be identified which are outlined below. If you think that you are having a relapse then the first thing you should do is contact your MS nurse.

        Types of relapse

        Optic neuritis

        • Inflammation of the optic nerve
        • Reduced vision in one eye
        • Feels like everything is fading away (colours desaturating)
        • Can have a black spot (scotoma) in the middle of the visual field
        • Can have pain on moving the eye

        Transverse myelitis

        • Inflammation of the spine
        • Tingling, numbness and weakness in one or both legs, one arm and leg, all four limbs, rarely, one arm
        • Bladder and/or bowel involvement

        Brainstem or cerebellar relapse

        • Double vision which goes away when covering or closing one eye
        • Balance problems
        • Coordination problems
        • Slurred speech

        Last reviewed: 04 December 2024