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17 Alpha Hydroxyprogesterone (17-OHP)

Clinical Biochemistry

Sample and container requirements

Serum (preferred) Lithium Heparin Plasma (paediatrics only)

Minimum volume required

300 µL serum/plasma

Special requirements

Time of collection MUST be stated.

Patient preparation

No specific patient preparation is required. Specimens from neonates for 17-OHP analysis should not be collected until 48 hours after birth and prior to any steroid therapy being commenced.

Sample viability

Turnaround time

5 working days

Reference range

Adults: Adult males: 1.2 – 3.7 nmol/L Adult females: 0.6 – 4.0 nmol/L (follicular phase) and 1.0 – 6.0 nmol/L (luteal phase) Paediatrics: Neonates (>48 hrs): <8.0 nmol/L (For neonates please record gestational age, birth weight and sex. Premature or small babies can have inappropriately high values.) Tanner stage 1 males/females: <5.0 nmol/L (Source: locally derived)

Clinical guidance

Please refer to LabTestsOnlineUK to learn more about 17-OHP. https://labtestsonline.org.uk/tests/17-hydroxyprogesterone

Notes

Images to go here

This information was last updated on 19 August 2026