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        aHUS Testing

        Clinical Biochemistry

        Sample and container requirements

        Sample types depends on the analyte and pathyways tested. For a new aHUS referall (ADAMTS13 not required): 1-2 x 5 mL EDTA for plasma, 2 x 7 mL SST for serum, and 2 x 5 mL EDTA. For new aHUS referral (including ADAMTS13): 1-2 x 5 mL EDTA for plasma, 2 x 7 mL SST for serum, 2 x 5 mL EDTA, and 2 x 2.7 mL sodium citrate for plasma. For aHUS genetics and FHAA, 2 x 5 mL EDTA and 1 x 5 mL clotted SST. For complement genotyping requests, 2 x 5 mL EDTA and 1 x 5 mL clotted SST. These should be agreed with the aHUS on call Consultant.

        Minimum volume required

        See form.

        Special requirements

        Please contact the Duty Biochemist the day prior to collection of samples. Take the samples to the laboratory within 15 minutes of sampling.

        Patient preparation

        None

        Sample viability

        Turnaround time

        Varies depending on analyte assessed, please refer to referral laboratory website: https://laboratories.newcastle-hospitals.nhs.uk/test-directory/ahus/

        Reference range

        Please refer to report for reference ranges.

        Clinical guidance

        Please follow the link below to the referral laboratory website for more information: https://www.atypicalhus.co.uk/clinician/

        Notes

        Sent to Newcastle Freeman Hospital

        Images to go here

        This information was last updated on 19 August 2026