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Alpha-fetoprotein (AFP)

Clinical Biochemistry

Sample and container requirements

Serum Lithium Heparin Plasma (paediatrics only)

Minimum volume required

Special requirements

None

Patient preparation

None

Sample viability

Turnaround time

This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

Reference range

0.7 – 7.3 kU/L (when used as a tumour marker) (Source: Abbott Diagnostics)

Clinical guidance

Alpha-fetoprotein (AFP) is used in the detection and monitoring of primary liver cell carcinomas which often develop secondary to liver cirrhosis or chronic hepatitis. Please refer to LabTestsOnlineUK to learn more about AFP. https://labtestsonline.org.uk/tests/afp-tumour-marker-test

Notes

AFP should not be used as a cancer screening test.

Images to go here

This information was last updated on 19 August 2026