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Angiotensin Converting Enzyme (ACE)

Clinical Biochemistry

Sample and container requirements

Serum Lithium Heparin Plasma (paediatrics only)

Minimum volume required

260 µL serum/plasma

Special requirements

None

Patient preparation

ACE activity testing should not be performed in patients treated for hypertension with ACE inhibitors

Sample viability

Turnaround time

This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

Reference range

Up to 18 years: 33 – 112 IU/L Adults: 20 – 70 IU/L (Source: Bühlmann Group)

Clinical guidance

Angiotensin converting enzyme (ACE) is an enzyme which helps regulate blood pressure. it can be used to help diagnose and monitor sarcoidosis in some patients. Please refer to LabTestsOnlineUK to learn more about ACE. https://labtestsonline.org.uk/tests/ace

Notes

Do not use EDTA plasma as EDTA inhibits ACE activity.

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This information was last updated on 19 August 2026