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        Angiotensin Converting Enzyme (ACE)

        Clinical Biochemistry

        Sample and container requirements

        Serum Lithium Heparin Plasma (paediatrics only)

        Minimum volume required

        260 µL serum/plasma

        Special requirements

        None

        Patient preparation

        ACE activity testing should not be performed in patients treated for hypertension with ACE inhibitors

        Sample viability

        Turnaround time

        This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

        Reference range

        Up to 18 years: 33 – 112 IU/L Adults: 20 – 70 IU/L (Source: Bühlmann Group)

        Clinical guidance

        Angiotensin converting enzyme (ACE) is an enzyme which helps regulate blood pressure. it can be used to help diagnose and monitor sarcoidosis in some patients. Please refer to LabTestsOnlineUK to learn more about ACE. https://labtestsonline.org.uk/tests/ace

        Notes

        Do not use EDTA plasma as EDTA inhibits ACE activity.

        Images to go here

        This information was last updated on 19 August 2026