Pathology tests database

Sample and container requirements

Serum (both plain and gel tubes suitable for analysis)

Minimum volume required

800 µL serum

Special requirements

None

Patient preparation

None. Thyroid function tests should be done at same time.

Sample viability

Turnaround time

2 days

Reference range

Positive: ≥4.11 IU/L Negative: <4.11 IU/L (Source: Abbott Diagnostics)

Clinical guidance

Please refer to LabTestsOnlineUK to learn more about anti-thyroglobulin antibodies. https://labtestsonline.org.uk/tests/thyroid-antibodies

Notes

For UHB patients, we currently use an Abbott Alinity immunometric assay (TgIMA) as our front line test for thyroglobulin, along with Thyroglobulin antibodies testing. For samples with positive TgAb, thyroglobulin by radioimmunoassay (TgRIA) is then automatically added on. External users may request the full testing pathway used for internal UHB patients (TgIMA and TgAb initially, with TgRIA added if antibody positive), or they may request only the TgRIA assay. Please make it clear on the request form which assay(s) are required. If looking for autoimmune thyroid disease please see thyroid peroxidase antibodies (TPOAb) or TSH-receptor antibodies (TSHAb) pages.