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        Chromogranin A/B

        Clinical Biochemistry

        Sample and container requirements

        EDTA Plasma

        Minimum volume required

        1 mL plasma

        Special requirements

        Fasting sample. Centrifuge the blood within 30 minutes of venepuncture. Send frozen.

        Patient preparation

        Fasting sample (6 - 8 hours) required.

        Sample viability

        Turnaround time

        28 days

        Reference range

        Please refer to report for reference ranges.

        Clinical guidance

        Please follow the link below to the referral laboratory website for more information: https://www.nwlpathology.nhs.uk/test/chromagranin-a/ Please note, chromogranin B does not generally offer any additional clinical utility. Requesting chromogranin A measurement is sufficient for the investigation and monitoring of neuroendocrine tumours. Specimen requirements for chromogranin B measurement are the same as for chromogranin A. Monaghan, P.J., Lamarca, A., Valle, J.W., Hubner, R.A., Mansoor, W., Trainer, P.J. and Darby, D., 2016. Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours. Clinical endocrinology, 84(3), pp.348-352.

        Notes

        Sent to Charing Cross Hospital

        Images to go here

        This information was last updated on 19 August 2026