Folate
Clinical Biochemistry
Sample and container requirements
Serum Lithium Heparin Plasma (paediatrics only)
Minimum volume required
75 µL serum/plasma
Special requirements
None
Patient preparation
Samples from patients receiving high biotin doses (i.e. >5 mg/day) should be taken at least 8 hours post-dose. Patients receiving treatment with methotrexate or leucovorin are contraindicated due to cross reactivity of folate binding proteins with these compounds.
Sample viability
Turnaround time
This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.
Reference range
3.1 – 20.5 µg/L. (Source: Abbott Diagnostics)
Clinical guidance
Folate plays an essential role in the formation of DNA and RNA, the function of vitamin B12, the formation of haem, and the formation of red and white blood cells. Please refer to LabTestsOnlineUK to learn more about folate. https://labtestsonline.org.uk/tests/vitamin-b12-and-folate
Notes
Images to go here
This information was last updated on 19 August 2026