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        High-Density Lipoprotein Cholesterol (HDL)

        Clinical Biochemistry

        Sample and container requirements

        Serum Lithium Heparin Plasma (paediatrics only)

        Minimum volume required

        75 µL serum/plasma

        Special requirements

        None

        Patient preparation

        Fasting sample is recommended.

        Sample viability

        Turnaround time

        This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

        Reference range

        Negative risk factor for heart disease ≥ 1.55 mmol/L (Source: Abbott Diagnostics)

        Clinical guidance

        HDL cholesterol forms part of the standard lipid panel in blood. HDL cholesterol testing, together with total cholesterol, LDL and triglycerides, is used to screening for atherosclerotic risk and in the diagnosis and treatment of disorders involving elevated cholesterol levels as well as lipid and lipoprotein metabolic disorders. Please refer to LabTestsOnlineUK to learn more about HDL Cholesterol. https://labtestsonline.org.uk/tests/hdl-cholesterol-test Further information: NICE Lipid Modification Guidelines (NG238): https://www.nice.org.uk/guidance/ng238

        Notes

        Images to go here

        This information was last updated on 19 August 2026