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        Lactate (CSF)

        Clinical Biochemistry

        Sample and container requirements

        Fluoride oxalate tube Plain universal container

        Minimum volume required

        250 µL CSF

        Special requirements

        Preferably tap #2 Sent immediately to the laboratory (not via pod system, take by hand to specimen reception)

        Patient preparation

        No specific patient preparation required

        Sample viability

        Turnaround time

        This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

        Reference range

        Neonates (≤28 days): 0.9 – 2.5 mmol/L Infants & Children (>28 days – <19 years): 1.0 – 2.2 mmol/L Adults (≥19 years): 1.1 – 2.4 mmol/L (Source: Leen et al. PLOS One 2012)

        Clinical guidance

        Raised levels of CSF lactate may occur with severe cerebral hypoxia or genetic lactic acidosis, intracranial haemorrhage, bacterial meningitis and epilepsy. Please refer to LabTestsOnlineUK to learn more about lactate. https://labtestsonline.org.uk/tests/lactate

        Notes

        Images to go here

        This information was last updated on 19 August 2026