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        Theophylline

        Clinical Biochemistry

        Sample and container requirements

        Serum Lithium Heparin Plasma (paediatrics only)

        Minimum volume required

        Special requirements

        None

        Patient preparation

        Samples should be taken at trough drug levels by collecting a sample prior to the next dose.

        Sample viability

        Turnaround time

        This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours. The test can be ordered as an urgent request.

        Reference range

        10 – 20 mg/L (Source: Pathology Harmony Recommendations)

        Clinical guidance

        Theophylline is an oral bronchodilator with a narrow therapeutic window. It is used in the treatment of conditions such as asthma and chronic obstructive pulmonary disease (COPD). Please refer to LabTestsOnlineUK to learn more about theophylline. https://labtestsonline.org.uk/tests/theophylline-and-caffeine

        Notes

        Images to go here

        This information was last updated on 19 August 2026