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Theophylline

Clinical Biochemistry

Sample and container requirements

Serum Lithium Heparin Plasma (paediatrics only)

Minimum volume required

Special requirements

None

Patient preparation

Samples should be taken at trough drug levels by collecting a sample prior to the next dose.

Sample viability

Turnaround time

This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours. The test can be ordered as an urgent request.

Reference range

10 – 20 mg/L (Source: Pathology Harmony Recommendations)

Clinical guidance

Theophylline is an oral bronchodilator with a narrow therapeutic window. It is used in the treatment of conditions such as asthma and chronic obstructive pulmonary disease (COPD). Please refer to LabTestsOnlineUK to learn more about theophylline. https://labtestsonline.org.uk/tests/theophylline-and-caffeine

Notes

Images to go here

This information was last updated on 19 August 2026