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Total Protein (Urine)

Clinical Biochemistry

Sample and container requirements

Plain Spot Urine Plain 24 hr Urine

Minimum volume required

Special requirements

None

Patient preparation

None

Sample viability

Turnaround time

This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.

Reference range

0.01 – 0.14 g/L <0.15 g/24 hr (Source: Abbott Diagnostics)

Clinical guidance

Protein measurements in urine are used in the diagnosis and treatment of renal and heart disease which are characterised by proteinuria or albuminuria. Proteinuria is usually first detected by a positive reaction for protein using a urine dip-stick. A ‘trace’ protein corresponds to a protein concentration of approximately 0.3 g/L and will prompt confirmation before further investigation. Proteinuria in excess of 2 g/24 hr is virtually always pathological and usually signifies glomerular disease.

Notes

Interference from haemolysis – do not analyse blood-stained specimens.

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This information was last updated on 19 August 2026