Urea (Urine)
Clinical Biochemistry
Sample and container requirements
Plain Spot Urine Plain 24 hr Urine
Minimum volume required
Special requirements
None
Patient preparation
None
Sample viability
Turnaround time
This assay is run throughout the day and night. The in-lab turnaround time is normally less than 24 hours.
Reference range
428 – 714 mmol/24 hr (Source: Abbott Diagnostics)
Clinical guidance
Catabolism of proteins and amino acids results in the formation of urea, which is predominantly cleared from the body by the kidneys. Measurement of urinary urea may be used as a measure of protein breakdown in the body. Low levels usually indicate malnutrition or renal dysfunction with high levels indicating excess protein intake or an increase in protein catabolism.
Notes
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This information was last updated on 19 August 2026