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        Complement anti C1q antibodies

        Immunology

        Sample and container requirements

        Serum

        Minimum volume required

        4 ml Blood

        Special requirements

        none

        Patient preparation

        None

        Sample viability

        Store at 4oC prior to sending to referral lab

        Turnaround time

        2 weeks

        Reference range

        0 – 20 units/ml

        Clinical guidance

        Autoantibodies against C1q are a major criterion in the diagnosis of hypocomplementaemic urticarial vasculitis. They are also found in up to 50% of SLE patients and 95% of patients with lupus nephritis. C1q antibodies may be useful for assessing the risk of renal flares, and also for monitoring the effectiveness of immunosuppressive treatment in active lupus nephritis. https://sheffieldlaboratorymedicine.nhs.uk/search-test.php?search=2976&testname=C1Q%20Antibodies

        Notes

        specimen referred to Sheffield

        Images to go here

        This information was last updated on 19 August 2026