Complement anti C1q antibodies
Immunology
Sample and container requirements
Serum
Minimum volume required
4 ml Blood
Special requirements
none
Patient preparation
None
Sample viability
Store at 4oC prior to sending to referral lab
Turnaround time
2 weeks
Reference range
0 – 20 units/ml
Clinical guidance
Autoantibodies against C1q are a major criterion in the diagnosis of hypocomplementaemic urticarial vasculitis. They are also found in up to 50% of SLE patients and 95% of patients with lupus nephritis. C1q antibodies may be useful for assessing the risk of renal flares, and also for monitoring the effectiveness of immunosuppressive treatment in active lupus nephritis. https://sheffieldlaboratorymedicine.nhs.uk/search-test.php?search=2976&testname=C1Q%20Antibodies
Notes
specimen referred to Sheffield
Images to go here
This information was last updated on 19 August 2026