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CSF Isoelectric focusing for oligoclonal bands

Immunology

Sample and container requirements

Paired CSF and serum sample

Minimum volume required

0.5 mL CSF + 4 ml Blood

Special requirements

It is essential that a serum sample is provided at the same time that the CSF is taken to allow correct interpretation of results

Patient preparation

None

Sample viability

Store at 4oC

Turnaround time

10 days

Reference range

negative

Clinical guidance

Some indications: Demyelinating conditions e.g. MS Other inflammatory states e.g. SLE, Neurosarcoid https://labtestsonline.org.uk/tests/csf-analysis

Notes

Images to go here

This information was last updated on 19 August 2026