Pathology tests database

Sample and container requirements

Serum

Minimum volume required

4 ml Blood

Special requirements

None

Patient preparation

None

Sample viability

Store at 4oC

Turnaround time

14 days

Reference range

Interperative assay , results reported as positive, negative or equivocal. 

Clinical guidance

The EUROLINE Autoimmune Inflammatory Myopathies 16 Ag (IgG) measures IgG autoantibodies to 15 different antigens: MI-2α, Mi-2β, Ku, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro-52,TIF-1γ, MDA5, NXP2 and SAE1 in serum or plasma. It is primarily used for the diagnosis of dermato- and polymyositis, idiopathic myositis, anti-synthetase syndrome and overlapping syndrome. Myositis is an inflammatory disease of skeletal muscles, which may be hereditary or can be triggered by infections, toxins or immune system disorders. Autoimmune myostides occur with an incidence of 0.1 to 1/100,000/year, a prevalence of 1 to 6/100,000 and a male: female ratio of 1:2.

Notes