Pathology tests database

Sample and container requirements

Serum

Minimum volume required

4 ml Blood

Special requirements

None

Patient preparation

None

Sample viability

Store at 4oC

Turnaround time

14 days

Reference range

<14 = Negative 14-20 = Borderline >20 = Positive results between 3 and 19.9 will be tested via IFA test at UoB

Clinical guidance

Phospholipase A2 receptor is the target autoantigen in idiopathic membranous nephropathy (IMN). Antibodies to PLA2r are found in up to 75% of patients with IMN naive to immunosuppression and can be used as a diagnostic marker for IMN. PLA2r antibodies are found to be high in active disease and low/normal in complete remission and can be used to monitor disease activity.

Notes