Pathology tests database

Sample and container requirements

Serum Please note Lithium Heparin samples are unsuitable for the measurement of Tissue Transglutaminase antibodies ( IgA and IgG)

Minimum volume required

4 ml Blood

Special requirements

None

Patient preparation

None

Sample viability

Stored at 4oC

Turnaround time

7 days

Reference range

Negative = <7 U/mL Weak positive = 7-10 U/mL Positive = >10 U/mL Normal result = Negative

Clinical guidance

Some indications: Coeliac Disease, Dermatitis, Herpetiformis

Notes

Patients with known or suspected IgA deficiency will have TTg IgG antibodies tested. In addition patients with suspected IgA deficiency will also have Immunoglobulins IgA, IgG and IgM levels measured in line with NICE guidelines All positive TTG results are confirmed by Endomysial antibody assay.